The successful clone:: the vector of dissemination of resistance in Streptococcus pneumoniae

被引：70

作者：

Klugman, KP

机构：

[1] Emory Univ, Dept Int Hlth, Rollins Sch Publ Hlth, Sch Med, Atlanta, GA 30322 USA

[2] Emory Univ, Sch Med, Div Infect Dis, Atlanta, GA 30322 USA

[3] MRC, NHLS, Wits Resp & Meningeal Patholgens Res Unit, Johannesburg, South Africa

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2002年 / 50卷

关键词：

D O I：

10.1093/jac/dkf500

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A small number of pneumococcal clones dominate the population of anti biotic-resistant pneumococci. The emergence of fluoroquinolone resistance in these clones predicts the dissemination of fluoroquinolone resistance in countries where the clones are present and community use of fluoroquinolones for respiratory infections is common. The molecular basis of resistance to a number of classes of antimicrobials can be used to predict the likelihood of dissemination of the resistance genes.

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页码：1 / 5

页数：5

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