Flavone-rich maize: an opportunity to improve the nutritional value of an important commodity crop

被引:57
作者
Casas, Maria I. [1 ,2 ,3 ]
Duarte, Silvia [3 ,4 ]
Doseff, Andrea I. [3 ,4 ]
Grotewold, Erich [1 ,3 ]
机构
[1] Ohio State Univ, Ctr Appl Plant Sci, Columbus, OH 43210 USA
[2] Ohio State Univ, Mol Cellular & Dev Biol Grad Program, Columbus, OH 43210 USA
[3] Ohio State Univ, Dept Mol Genet, Columbus, OH 43210 USA
[4] Ohio State Univ, Heart & Lung Res Inst, Dept Internal Med, Div Pulmonary Allergy Crit Care & Sleep, Columbus, OH 43210 USA
来源
FRONTIERS IN PLANT SCIENCE | 2014年 / 5卷
基金
美国国家科学基金会; 美国食品与农业研究所;
关键词
maize; metabolism; nutrition; inflammation; cancer; nutritional disparity; P-GENE; MEDITERRANEAN DIET; CELERY; MAYSIN; CORN; BIOSYNTHESIS; FURANOCOUMARINS; IDENTIFICATION; TRANSCRIPTION; ACCUMULATION;
D O I
10.3389/fpls.2014.00440
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Agricultural outputs have resulted in food production continuously expanding. To satisfy the needs of a fast growing human population, higher yields, more efficient food processing, and food esthetic value, new crop varieties with higher caloric intake have and continue to be developed, but which lack many phytochemicals important for plant protection and adequate human nutrition. The increasing incidence of chronic diseases such as obesity, diabetes and cardiovascular diseases, combined with social disparity worldwide prompted the interest in developing enhanced crops that can simultaneously address the two sides of the current malnutrition sword, increasing yield while providing added nutritional value. Flavones, phytochemicals associated with the beneficial effects of the Mediterranean diet, have potent anti-inflammatory and anti-carcinogenic activities. However, many Mediterranean diet-associated vegetables are inaccessible, or lowly consumed, in many parts of the world. Maize is the most widely grown cereal crop, yet most lines used for hybrid maize production lack flavones. As a first step toward a sustainable strategy to increasing the nutritional value of maize-based diets, we investigated the accumulation and chemical properties of flavones in maize seeds of defined genotypes. We show that the pericarps of the P1-rr genotype accumulate flavones at levels comparable to those present in some flavone-rich vegetables, and are mostly present in their C- and O-glycosylated forms. Some of these glycosides can be readily converted into the corresponding more active health beneficial aglycones during food processing. Our results provide evidence that nutritionally beneficial flavones could be re-introduced into elite lines to increase the dietary benefits of maize.
引用
收藏
页数:11
相关论文
共 55 条
[1]  
Anderson EG, 1924, GENETICS, V9, P442
[2]  
ANDERSON EG, 1921, THESIS CORNELL U ITH
[3]   UV/Visible spectra of natural polyphenols: A time-dependent density functional theory study [J].
Anouar, El Hassane ;
Gierschner, Johannes ;
Duroux, Jean-Luc ;
Trouillas, Patrick .
FOOD CHEMISTRY, 2012, 131 (01) :79-89
[4]   Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets [J].
Arango, Daniel ;
Morohashi, Kengo ;
Yilmaz, Alper ;
Kuramochi, Kouji ;
Parihar, Arti ;
Brahimaj, Bledi ;
Grotewold, Erich ;
Doseff, Andrea I. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (24) :E2153-E2162
[5]  
BAILEY D. M., 1938, PROC AMER SOC HORT SCI, V36, P555
[6]   PSORALEN AND OTHER LINEAR FUROCOUMARINS AS PHYTOALEXINS IN CELERY [J].
BEIER, RC ;
OERTLI, EH .
PHYTOCHEMISTRY, 1983, 22 (11) :2595-2597
[7]  
Bligh S.W.A., 2013, Natural Products, P2107, DOI DOI 10.1007/978-3-642-22144-6_97
[8]   The Mediterranean diet: The reasons for a success [J].
Bonaccio, Marialaura ;
Iacoviello, Licia ;
de Gaetano, Giovanni .
THROMBOSIS RESEARCH, 2012, 129 (03) :401-404
[9]   The C-Glycosylation of Flavonoids in Cereals [J].
Brazier-Hicks, Melissa ;
Evans, Kathryn M. ;
Gershater, Markus C. ;
Puschmann, Horst ;
Steel, Patrick G. ;
Edwards, Robert .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (27) :17926-17934
[10]   Maize silk maysin concentration and corn earworm antibiosis: QTLs and genetic mechanisms [J].
Byrne, PF ;
McMullen, MD ;
Wiseman, BR ;
Snook, ME ;
Musket, TA ;
Theuri, JM ;
Widstrom, NW ;
Coe, EH .
CROP SCIENCE, 1998, 38 (02) :461-471