Length-dependent uptake of DNA-wrapped single-walled carbon nanotubes

被引：132

作者：

Becker, Matthew L. ^{[1
]}

Fagan, Jeffrey A. ^{[1
]}

Gallant, Nathan D. ^{[1
]}

Bauer, Barry J. ^{[1
]}

Bajpai, Vardan ^{[1
]}

Hobbie, Erik K. ^{[1
]}

Lacerda, Silvia H. ^{[1
]}

Migler, Kalman B. ^{[1
]}

Jakupciak, John P. ^{[1
]}

机构：

[1] Natl Inst Stand & Technol, Polymers Div, Gaithersburg, MD 20899 USA

来源：

ADVANCED MATERIALS | 2007年 / 19卷 / 07期

关键词：

D O I：

10.1002/adma.200602667

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A length threshold for cell uptake of DNA-wrapped single-walled carbon nanotubes (SWNTs) by human lung fibroblasts (IMR90) is identified. Competitive uptake experiments with well-defined and characterized length fractions show that SWNTs above the length threshold are excluded from the cell, whereas SWNTs labeled with Cy3-derivatized DNA below the threshold are able to access the cell interior, as shown in the fluorescence image and on the cover.

引用

页码：939 / +

页数：8

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