Novel enantioselective synthesis of (2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine (DCG-IV)

被引:14
作者
Marinozzi, M [1 ]
Pellicciari, R [1 ]
机构
[1] Univ Perugia, Dipartimento Chim & Tecnol Farm, I-06123 Perugia, Italy
关键词
metabotropic glutamate receptors; (carboxycyclopropyl)glycines; asymmetric cyclopropanation;
D O I
10.1016/S0040-4039(00)01629-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel enantioselective synthesis of (2S,2'R,3'R)-2-(2',3'-dicarboxycyclopropyl)glycine (DCG-IV), a potent group II mGluRs agonist is described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:9125 / 9128
页数:4
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