Genetically modified mouse models in studies on cutaneous wound healing

被引:27
作者
Scheid, A [1 ]
Meuli, M
Gassmann, M
Wenger, RH
机构
[1] Univ Zurich, Childrens Hosp, Dept Surg, CH-8000 Zurich, Switzerland
[2] Univ Zurich Irchel, Inst Physiol, CH-8000 Zurich, Switzerland
[3] Univ Lubeck, Inst Physiol, D-23538 Lubeck, Germany
关键词
D O I
10.1017/S0958067000021035
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Genetically modified mice have become an invaluable tool in modern biomedical and basic research. This review provides an overview of knockout and transgenic mice studied with regard to their cutaneous wound healing properties. In addition, several gene transfer studies are briefly introduced, which have further highlighted our knowledge on individual gene function in wound healing.
引用
收藏
页码:687 / 704
页数:18
相关论文
共 176 条
[1]   Augmented inflammatory responses and altered wound healing in cathepsin G-deficient mice [J].
Abbott, RE ;
Corral, CJ ;
MacIvor, DM ;
Lin, XH ;
Ley, TJ ;
Mustoe, TA .
ARCHIVES OF SURGERY, 1998, 133 (09) :1002-1006
[2]   FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase [J].
AdamKlages, S ;
Adam, D ;
Wiegmann, K ;
Struve, S ;
Kolanus, W ;
SchneiderMergener, J ;
Kronke, M .
CELL, 1996, 86 (06) :937-947
[3]   Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation [J].
Andersen, B ;
Weinberg, WC ;
Rennekampff, O ;
McEvilly, RJ ;
Bermingham, JR ;
Hooshmand, F ;
Vasilyev, V ;
Hansbrough, JF ;
Pittelkow, MR ;
Yuspa, SH ;
Rosenfeld, MG .
GENES & DEVELOPMENT, 1997, 11 (14) :1873-1884
[4]  
[Anonymous], 2014, SCI TRANSL MED, DOI DOI 10.1126/scitranslmed.3009337
[5]   CD44 IS THE PRINCIPAL CELL-SURFACE RECEPTOR FOR HYALURONATE [J].
ARUFFO, A ;
STAMENKOVIC, I ;
MELNICK, M ;
UNDERHILL, CB ;
SEED, B .
CELL, 1990, 61 (07) :1303-1313
[6]   Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization [J].
Asahara, T ;
Masuda, H ;
Takahashi, T ;
Kalka, C ;
Pastore, C ;
Silver, M ;
Kearne, M ;
Magner, M ;
Isner, JM .
CIRCULATION RESEARCH, 1999, 85 (03) :221-228
[7]   Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response [J].
Ashcroft, GS ;
Yang, X ;
Glick, AB ;
Weinstein, M ;
Letterio, JJ ;
Mizel, DE ;
Anzano, M ;
Greenwell-Wild, T ;
Wahl, SM ;
Deng, CX ;
Roberts, AB .
NATURE CELL BIOLOGY, 1999, 1 (05) :260-266
[8]   The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited fibroblasts [J].
Atit, RP ;
Crowe, MJ ;
Greenhalgh, DG ;
Wenstrup, RJ ;
Ratner, N .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1999, 112 (06) :835-842
[9]   COLORECTAL HYPERPLASIA AND INFLAMMATION IN KERATIN 8-DEFICIENT EVB/N MICE [J].
BARIBAULT, H ;
PENNER, J ;
IOZZO, RV ;
WILSONHEINER, M .
GENES & DEVELOPMENT, 1994, 8 (24) :2964-2973
[10]   MIDGESTATIONAL LETHALITY IN MICE LACKING KERATIN-8 [J].
BARIBAULT, H ;
PRICE, J ;
MIYAI, K ;
OSHIMA, RG .
GENES & DEVELOPMENT, 1993, 7 (7A) :1191-1202