International Nosocomial Infection Control Consortium (INICC) report, data summary for 2003-2008, issued June 2009

被引：284

作者：

Rosenthal, Victor D. ^{[1
]}

Maki, Dennis G. ^{[2
]}

Jamulitrat, Silom ^{[3
]}

Medeiros, Eduardo A. ^{[4
]}

Todi, Subhash Kumar ^{[5
]}

Yepes Gomez, David ^{[6
]}

Leblebicioglu, Hakan ^{[7
]}

Abu Khader, Ilham ^{[8
]}

Miranda Novales, Maria Guadalupe ^{[9
]}

Berba, Regina ^{[10
]}

Ramirez Wong, Fernando Martin ^{[11
]}

Barkat, Amina ^{[12
]}

Requejo Pino, Osiel ^{[13
]}

Duenas, Lourdes ^{[14
]}

Mitrev, Zan ^{[15
]}

Hu Bijie ^{[16
]}

Gurskis, Vaidotas ^{[17
]}

Kanj, S. S. ^{[18
]}

Mapp, Trudell ^{[19
]}

Fernandez Hidalgo, Rosalia ^{[20
]}

Ben Jaballah, Nejla ^{[21
]}

Raka, Lul ^{[22
,23
]}

Gikas, Achilleas ^{[24
]}

Ahmed, Altaf ^{[25
]}

Le Thi Anh Thu ^{[26
]}

Guzman Siritt, Maria Eugenia ^{[27
]}

机构：

[1] INICC, Buenos Aires, DF, Argentina

[2] Univ Wisconsin, Sch Med, Madison, WI USA

[3] Songklanagarind Hosp, Songkhla, Thailand

[4] Hosp Sao Paulo, Sao Paulo, Brazil

[5] AMRI Hosp, Kolkata, India

[6] Clin CES, Medellin, Colombia

[7] Ondokuz Mayis Univ, Sch Med, Samsun, Turkey

[8] Jordan Univ Hosp, Amman, Jordan

[9] IMSS, Hosp Pediat CMN Siglo 21, Mexico City, DF, Mexico

[10] Philippine Gen Hosp, Manila, Philippines

[11] Hosp Maria Auxiliadora, Lima, Peru

[12] Childrens Hosp Rabat, Rabat, Morocco

[13] Hosp Univ Gral, Calixto, Garcia Havana, Cuba

[14] Hosp Nacl Ninos Benjamin Bloom, San Salvador, El Salvador

[15] Filip II Special Cardiosurg Hosp, Skopje, Macedonia

[16] Zhongshan Hosp, Shanghai, Peoples R China

[17] Kaunas Univ Med, Children Clin, Kaunas, Lithuania

[18] Amer Univ Beirut, Med Ctr, Beirut, Lebanon

[19] Clin Hosp San Fernando Panama, Panama City, Panama

[20] Hosp Clin Bibl, San Jose, Costa Rica

[21] Hop Enfants, Tunis, Tunisia

[22] Prishtina Univ, Natl Inst Publ Hlth Kosova, Prishtina, Serbia

[23] Prishtina Univ, Sch Med, Prishtina, Serbia

[24] Univ Hosp Heraklion, Iraklion, Greece

[25] Liaquat Natl Hosp, Karachi, Pakistan

[26] Cho Ray Hosp, Ho Chi Minh City, Vietnam

[27] Hosp Militar Dr Carlos Arvelo, Caracas, Venezuela

来源：

AMERICAN JOURNAL OF INFECTION CONTROL | 2010年 / 38卷 / 02期

关键词：

Hospital infection; nosocomial infection; health care-associated infection; INICC; International Nosocomial Infection Consortium; device-associated infection; antibiotic resistance; ventilator-associated pneumonia; catheter-associated urinary tract infection; central line-associated bloodstream infections; bloodstream infection; urinary tract infection; developing countries; limited resources countries; low income countries; network; INTENSIVE-CARE UNITS; BLOOD-STREAM INFECTIONS; NETWORK NHSN REPORT; PERFORMANCE FEEDBACK; SAFETY NETWORK; CONTROL PROGRAM; RATES; HOSPITALS; MORTALITY; EDUCATION;

D O I：

10.1016/j.ajic.2009.12.004

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We report the results of the International Infection Control Consortium (INICC) surveillance study from January 2003 through December 2008 in 173 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study, using Centers for Disease Control and Prevention (CDC) US National Healthcare Safety Network (NHSN; formerly the National Nosocomial Infection Surveillance system [NNIS]) definitions for device-associated health care-associated infection, we collected prospective data from 155,358 patients hospitalized in the consortium's hospital ICUs for an aggregate of 923,624 days. Although device utilization in the developing countries' ICUs was remarkably similar to that reported from US ICUs in the CDC's NHSN, rates of device-associated nosocomial infection were markedly higher in the ICUs of the INICC hospitals: the pooled rate of central venous catheter (CVC)-associated bloodstream infections (BSI) in the INICC ICUs, 7.6 per 1000 CVC-days, is nearly 3-fold higher than the 2.0 per 1000 CVC-days reported from comparable US ICUs, and the overall rate of ventilator-associated pneumonia (VAP) was also far higher, 13.6 versus 3.3 per 1000 ventilator-days, respectively, as was the rate of catheter-associated urinary tract infection (CAUTI), 6.3 versus 3.3 per 1000 catheter-days, respectively. Most strikingly, the frequencies of resistance of Staphylococcus aureus isolates to methicillin (MRSA) (84.1% vs 56.8%, respectively), Klebsiella pneumoniae to ceftazidime or ceftriaxone (76.1% vs 27.1%, respectively), Acinetobacter baumannii to imipenem (46.3% vs 29.2%, respectively), and Pseudomonas aeruginosa to piperacillin (78.0% vs 20.2%, respectively) were also far higher in the consortium's ICUs, and the crude unadjusted excess mortalities of device-related infections ranged from 23.6% (CVC-associated bloodstream infections) to 29.3% (VAP).

引用

页码：95 / U31

页数：12

共 33 条

[1] National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004 [J].