Maternal waist-to-hip ratio as a predictor of newborn size: Results of the Diana project

被引:46
作者
Brown, JE [1 ]
Potter, JD [1 ]
Jacobs, DR [1 ]
Kopher, RA [1 ]
Rourke, MJ [1 ]
Barosso, GM [1 ]
Hannan, PJ [1 ]
Schmid, LA [1 ]
机构
[1] UNIV MINNESOTA,SCH PUBL HLTH,DEPT PUBL HLTH NUTR,MINNEAPOLIS,MN 55454
关键词
body fat distribution; waist-to-hip ratio; preconception; pregnancy; infant birthweight;
D O I
10.1097/00001648-199601000-00011
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Location of body fat stores, as indicated by waist-to-hip circumference ratio (WHR), affects a variety of metabolic processes in women, and some of these changes could affect fetal growth during pregnancy. We tested the hypothesis that WHR affects fetal growth among 702 participants of the Diana Project, a prospective study designed to identify preconceptual exposures related to reproductive outcomes. We tested the effect of maternal WHR on the outcomes of infant birth weight, length, and head circumference in regressional models that included 16 variables such as maternal body mass index, duration of gestation, and pregnancy weight gain previously related to birthweight. Maternal WHR was related to each measure of newborn size. A 0.1-unit increase in WHR predicts a 120-gm greater birthweight, a 0.2-inch greater length, and a 0.3-cm greater head circumference. We conclude that WHR is related to fetal growth and that the effect of WHR on fetal growth may be mediated by metabolic alterations associated with a preponderance of central body fat stores or to other factors closely aligned with WHR. The common finding of an independent effect of prepregnancy BMI on birthweight may be largely attributable to maternal WHR.
引用
收藏
页码:62 / 66
页数:5
相关论文
共 34 条
[1]  
Nutrition during Pregnancy. 1. Weight Gain. II. Nutrient Supplements, (1990)
[2]  
Niswander K.R., Gorden M., The Women and Their Pregnancies, (1972)
[3]  
Taffel S., Factors Associated with low Birth Weight: United States, 1976. Series 21, 37, (1980)
[4]  
Brown J.E., Berdan K.W., Splett P., Robinson M., Harris L.J., Prenatal weight gains related to the birth of healthy-sized infants to low-income women, J Am Diet Assoc, 86, pp. 1679-1683, (1986)
[5]  
Goldenberg R.L., Davis R.O., Cliver S.P., Cutter O.R., Huffman H.J., Dubard M.B., Copper R.L., Maternal risk factors and their influence on fetal anthropometric measurements, Am J Obstet Gynecol, 168, pp. 1197-1205, (1993)
[6]  
McKeigue P.M., Pierpoint T., Ferrie J.E., Marmot M.G., Relationship of glucose intolerance and hyperinsulinaemia to body fat pattern in South Asians and Europeans, Diabetologia, 35, pp. 785-791, (1992)
[7]  
Heitmann B.L., The variation in blood lipid levels described by various measures of overall and abdominal obesity in Danish men and women aged 35-65 years, Eur J Clin Nutr, 46, pp. 597-605, (1992)
[8]  
Selby J.V., Austin M.A., Newman B., Zhang D., Quesenberry Jr. C.P., Mayer E.J., Krauss R.M., LDL subclass phenotypes and the insulin resistance syndrome in women, Circulation, 88, pp. 381-387, (1993)
[9]  
Campaigne B.N., Body fat distribution in females: Metabolic consequences and implications for weight loss, Med Sci Sports Exerc, 22, pp. 291-297, (1990)
[10]  
Dowling H.J., Pi-Sunyer F.X., Race-dependent health risks of upper body obesity, Diabetes, 42, pp. 537-543, (1993)