Stimulation of the MLR inhibits the discharge of dorsal horn neurons responsive to muscular contraction

被引：19

作者：

Degtyarenko, AM

Kaufman, MP

机构：

[1] Univ Calif Davis, Dept Internal Med, Div Cardiovasc Med, Davis, CA 95616 USA

[2] Univ Calif Davis, Dept Human Physiol, Davis, CA 95616 USA

来源：

BRAIN RESEARCH | 2000年 / 880卷 / 1-2期

关键词：

exercise; group III muscle afferent; cat; cardiovascular control;

D O I：

10.1016/S0006-8993(00)02738-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We found that electrical stimulation of the mesencephalic locomotor region (MLR) inhibited thp discharge of deep dorsal horn neurons receiving group III afferent input from the triceps surae muscles. In contrast, contraction of these muscles induced by electrical stimulation of the: tibial nerve activated these dorsal hum neurons. Our findings show that descending central motor commands can inhibit dorsal horn interneurons receiving input from group III afferents during exercise. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：178 / 182

页数：5

相关论文

共 18 条

[1] Responses of group III and IV muscle afferents to dynamic exercise [J].

Adreani, CM ;

Hill, JM ;

Kaufman, MP .

JOURNAL OF APPLIED PHYSIOLOGY, 1997, 82 (06) :1811-1817

[2] EFFECTS OF MIDBRAIN STIMULATION AND IONTOPHORETIC APPLICATION OF SEROTONIN, NORADRENALINE, MORPHINE AND GABA ON ELECTRICAL THRESHOLDS OF AFFERENT C-FIBER AND A-FIBER TERMINALS IN CAT SPINAL-CORD [J].

CARSTENS, E ;

GILLY, H ;

SCHREIBER, H ;

ZIMMERMANN, M .

NEUROSCIENCE, 1987, 21 (02) :395-406

[3] DIFFERENTIAL INHIBITORY EFFECTS OF MEDIAL AND LATERAL MIDBRAIN STIMULATION ON SPINAL NEURONAL DISCHARGES TO NOXIOUS SKIN HEATING IN THE CAT [J].

CARSTENS, E ;

KLUMPP, D ;

ZIMMERMANN, M .

JOURNAL OF NEUROPHYSIOLOGY, 1980, 43 (02) :332-342

[4] THE DISTRIBUTION OF AFFERENT-FIBERS FROM THE GASTROCNEMIUS-SOLEUS MUSCLE IN THE DORSAL HORN OF THE CAT, AS REVEALED BY THE TRANSPORT OF HORSERADISH-PEROXIDASE [J].

CRAIG, AD ;

MENSE, S .

NEUROSCIENCE LETTERS, 1983, 41 (03) :233-238

[5] Fictive locomotion and scratching inhibit dorsal horn neurons receiving thin fiber afferent input [J].

Degtyarenko, AM ;

Kaufman, MP .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2000, 279 (02) :R394-R403

[6] EXERCISE HYPERPNEA AND LOCOMOTION - PARALLEL ACTIVATION FROM THE HYPOTHALAMUS [J].

ELDRIDGE, FL ;

MILLHORN, DE ;

WALDROP, TG .

SCIENCE, 1981, 211 (4484) :844-846

[7] EFFECTS OF MECHANICAL AND CHEMICAL STIMULATION OF FINE MUSCLE AFFERENTS UPON PRIMATE SPINOTHALAMIC TRACT CELLS [J].

FOREMAN, RD ;

SCHMIDT, RF ;

WILLIS, WD .

JOURNAL OF PHYSIOLOGY-LONDON, 1979, 286 (JAN) :215-231

[8] DESCENDING CONTROL OF LUMBOSACRAL SPINAL-CORD FROM MESENCEPHALIC-LOCOMOTOR-REGION [J].

GRILLNER, S ;

SHIK, ML .

ACTA PHYSIOLOGICA SCANDINAVICA, 1973, 87 (03) :320-333

[9] RESPONSE BEHAVIOR OF CAT DORSAL HORN NEURONS RECEIVING INPUT FROM SKELETAL-MUSCLE AND OTHER DEEP SOMATIC TISSUES [J].

HOHEISEL, U ;

MENSE, S .

JOURNAL OF PHYSIOLOGY-LONDON, 1990, 426 :265-280

[10] TERMINATION PATTERNS OF IDENTIFIED GROUP-II AND GROUP-III AFFERENT-FIBERS FROM DEEP TISSUES IN THE SPINAL-CORD OF THE CAT [J].

HOHEISEL, U ;

LEHMANNWILLENBROCK, E ;

MENSE, S .

NEUROSCIENCE, 1989, 28 (02) :495-507