Cascades to substituted indoles

被引：76

作者：

Rainier, JD ^{[1
]}

Kennedy, AR ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 19期

关键词：

D O I：

10.1021/jo000831n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes the synthesis of dithioindoles from the free-radical cyclizations of arylisonitriles having pendant alkynes. Also described is the synthesis of substituted indoles and spiro-fused indoles from the coupling of dithioindoles with active hydrogen-containing compounds.

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页码：6213 / 6216

页数：4

相关论文

共 54 条

[1] THE PREPARATION OF PHENYL KETONES USING (PHENYLTHIO)PHENYL-(TRIMETHYLSILYL)METHYL-LITHIUM [J].

AGER, DJ .

TETRAHEDRON LETTERS, 1980, 21 (49) :4759-4762

[2] A NEW METHOD FOR CONVERTING ALKYL-HALIDES TO HOMOLOGOUS ALDEHYDES [J].

AGER, DJ ;

COOKSON, RC .

TETRAHEDRON LETTERS, 1980, 21 (17) :1677-1680

[3]

[Anonymous], 1883, BER DTSCH CHEM GES, DOI DOI 10.1002/CBER.188301602141

[4] THIOL-MEDIATED FREE-RADICAL CYCLIZATION OF ALKENYL AND ALKYNYL ISOCYANIDES [J].

BACHI, MD ;

BALANOV, A ;

BARNER, N .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (25) :7752-7758

[5] Synthesis of heterocycles by radical cyclisation [J].

Bowman, WR ;

Bridge, CF ;

Brookes, P .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2000, (01) :1-14

[6] Radical annulations with nitriles: Novel cascade reactions of cyano-substituted alkyl and sulfanyl radicals with isonitriles [J].

Camaggi, CM ;

Leardini, R ;

Nanni, D ;

Zanardi, G .

TETRAHEDRON, 1998, 54 (21) :5587-5598

[7] ORGANOALKALI COMPOUNDS BY RADICAL-ANION INDUCED REDUCTIVE METALATION OF PHENYL THIOETHERS [J].

COHEN, T ;

BHUPATHY, M .

ACCOUNTS OF CHEMICAL RESEARCH, 1989, 22 (04) :152-161

[8] ENANTIOSELECTIVE SYNTHESIS OF GAMMA-HYDROXYSILANES, 1,3-DIOLS AND CYCLOPROPANES BY REACTION OF A CHIRAL EPOXIDE WITH A RACEMIC ALPHA-SILYL ORGANOLITHIUM REAGENT [J].

COREY, EJ ;

CHEN, ZL .

TETRAHEDRON LETTERS, 1994, 35 (47) :8731-8734

[9] Novel mammalian cell cycle inhibitors, cyclotryprostatins A-D, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase [J].

Cui, CB ;

Kakeya, H ;

Osada, H .

TETRAHEDRON, 1997, 53 (01) :59-72

[10] Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus .1. Taxonomy, fermentation, isolation and biological properties [J].

Cui, CB ;

Kakeya, H ;

Okada, G ;

Onose, R ;

Osada, H .

JOURNAL OF ANTIBIOTICS, 1996, 49 (06) :527-533

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