Ligustolide A and B, two novel sesquiterpenes with rare skeletons and three 1,10-seco-guaianolide derivatives from Achillea ligustica

被引：65

作者：

Ahmed, AA

Gáti, T

Hussein, TA

Ali, AT

Tzakou, OA

Couladis, MA

Mabry, TJ

Tóth, G

机构：

[1] Budapest Univ Technol & Econ, Inst Gen & Analyt Chem, Hungarian Acad Sci, Tech Analyt Res Grp, H-1111 Budapest, Hungary

[2] Menia Univ, Fac Sci, Dept Chem, El Minia 61519, Egypt

[3] Univ Athens, Dept Pharmacognosy, GR-15771 Athens, Greece

[4] Univ Athens, Dept Pharm, GR-15771 Athens, Greece

[5] Univ Texas, Austin, TX 78712 USA

来源：

TETRAHEDRON | 2003年 / 59卷 / 21期

基金：

匈牙利科学研究基金会;

关键词：

ligustolide A and B; sesquiterpenes; Achillea ligustica;

D O I：

10.1016/S0040-4020(03)00572-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Achillea ligustica afforded two novel sesquiterpene lactones with rare 5/6/5 skeletons, three 1,10-seco-guaianolides and a chlorine-containing sesquiterpene lactone as well as six known compounds, including two monoterpenes, two guaianolides, one eudesmane and one secocaryophyllene derivative. The structures of the compounds were elucidated by extensive application of one- and two-dimensional NMR spectroscopy. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：3729 / 3735

页数：7

共 33 条

[1] IRREGULAR OXYGENATED MONOTERPENES FROM ACHILLEA-FRAGRANTISSIMA [J].

AHMED, AA ;

JAKUPOVIC, J ;

ELDIN, AAS ;

MELEK, FR .

PHYTOCHEMISTRY, 1990, 29 (04) :1322-1324

[2] Two highly oxygenated eudesmanes and 10 lignans from Achillea holosericea [J].

Ahmed, AA ;

Mahmoud, AA ;

Ali, ET ;

Tzakou, O ;

Couladis, M ;

Mabry, TJ ;

Gáti, T ;

Tóth, G .

PHYTOCHEMISTRY, 2002, 59 (08) :851-856

[3]

Ahmed AA, 1989, J NAT PROD, V20, P5

[4] A SECO-BIS-NORGUAIANOLIDE FROM ACHILLEA-PSEUDOALEPPICA [J].

APPENDINO, G ;

JAKUPOVIC, J ;

OZEN, HC ;

SCHUSTER, N .

PHYTOCHEMISTRY, 1993, 34 (04) :1171-1172

[5] A guaianolide and a germacranolide from Achillea santolina [J].

Balboul, BAAA ;

Ahmed, AA ;

Otsuka, H ;

Bando, M ;

Kido, M ;

Takeda, Y .

PHYTOCHEMISTRY, 1997, 46 (06) :1045-1049

[6]

BOHLMANN F, 1984, LIEBIGS ANN CHEM, P503

[7] NATURALLY-OCCURRING TERPENE DERIVATIVES .454. SESQUITERPENE LACTONES AND OTHER CONSTITUENTS FROM TANACETUM-PARTHENIUM [J].

BOHLMANN, F ;

ZDERO, C .

PHYTOCHEMISTRY, 1982, 21 (10) :2543-2549

[8]

Breitmaier E., 1987, Carbon-13 NMR spectroscopy, V3rd, P288

[9] GUAIANOLIDES AND OTHER CONSTITUENTS OF ACHILLEA-LIGUSTICA [J].

BRUNO, M ;

HERZ, W .

PHYTOCHEMISTRY, 1988, 27 (06) :1871-1872

[10]

EEKAN Z, 1958, COLLECT CZECH CHEM C, V24, P1554

← 1 2 3 4 →