Evaluation of the variables that affect resolution in delayed extraction MALDI-TOF

被引：26

作者：

Barbacci, DC ^{[1
]}

Edmondson, RD ^{[1
]}

Russell, DH ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Chem, Lab Biol Mass Spectrometry, College Stn, TX 77843 USA

来源：

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY | 1997年 / 165卷

关键词：

delayed ion formation; initial velocity; initial position; ionization process(es); computer modeling;

D O I：

10.1016/S0168-1176(97)00169-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

The effects of the various experimental parameters on mass resolution of MALDI-TOF and MALDI with delayed extraction are evaluated using an ion flight simulation program. With this program we are able to examine the effects of initial position, initial velocity, delay time, and ion kinetic energy on the line width of TOF spectra. A description of the model is presented as well as data showing the effects of DE parameters on the arrival time distribution of ions in linear and reflectron TOF mass spectra. (C) 1997 Elsevier Science B.V.

引用

页码：221 / 235

页数：15

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