Association of a polymorphism of the endothelial constitutive nitric oxide synthase gene with myocardial infarction in the Japanese population

被引：127

作者：

Ichihara, S

Yamada, Y

Fujimura, T

Nakashima, N

Yokota, M

机构：

[1] Nagoya Univ, Sch Med, Dept Clin Lab Med, Showa Ku, Nagoya, Aichi 466, Japan

[2] Nagoya Univ, Sch Med, Dept Internal Med, Nagoya, Aichi 466, Japan

[3] Natl Inst Longev Sci, Dept Geriatr Res, Aichi, Japan

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1998年 / 81卷 / 01期

关键词：

D O I：

10.1016/S0002-9149(97)10806-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We investigated the association between variations in the endothelial constitutive nitric oxide synthase (ecNOS) gene and the presence of myocardial infarction. The results indicate that the mutant allele (ecNOS'4a) is an independent risk factor for myocardial infarction in the Japanese population, especially in those lacking other conventional risk factors.

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页码：83 / +

页数：5

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