Peptide nucleic acid (PNA) - From DNA recognition to antisense and DNA structure

被引:18
作者
Nielsen, PE [1 ]
机构
[1] Univ Copenhagen, Panum Inst, Dept Med Biochem & Genet, Ctr Biomol Recognit,Biochem Lab B, DK-2200 Copenhagen N, Denmark
关键词
PNA; peptide nucleic acid; antisense; nucleic acid hybridization;
D O I
10.1016/S0301-4622(97)00019-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The biophysical and biological properties of PNA (peptide nucleic acid) is briefly reviewed with special emphasis on recent three dimensional structures of PNA-nucleic acid complexes and on structure-activity relations in terms of nucleic acid hybridization properties. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:103 / 108
页数:6
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