Olanzapine treatment of anorexia nervosa: A retrospective study

被引：57

作者：

Malina, A ^{[1
]}

Gaskill, J ^{[1
]}

McConaha, C ^{[1
]}

Frank, GK ^{[1
]}

LaVia, M ^{[1
]}

Scholar, L ^{[1
]}

Kaye, WH ^{[1
]}

机构：

[1] Univ Pittsburgh, Ctr Med, Western Psychiat Inst & Clin, Dept Psychiat, Pittsburgh, PA 15213 USA

来源：

INTERNATIONAL JOURNAL OF EATING DISORDERS | 2003年 / 33卷 / 02期

关键词：

olanzapine; weight gain; anorexia nervosa; psychiatric disorder;

D O I：

10.1002/eat.10122

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Background: Recent reports raise the possibility that olanzapine, which commonly causes weight gain in non-eating-disordered subjects, assisted weight gain and mood during refeeding in anorexia nervosa (AN) patients. Methods: Eighteen AN subjects who engaged in open treatment with olanzapine were retrospectively questioned about their response. Results: Subjects reported a significant reduction in anxiety, difficulty eating, and core eating disorder symptoms after taking olanzapine. Discussion: These data lend support to the possibility that olanzapine may be useful in AN patients. Conclusion: A controlled trial is necessary to prove that olanzapine is efficacious. (C) 2003 by Wiley Periodicals, Inc.

引用

页码：234 / 237

页数：4

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