Exacerbations in cystic fibrosis •1:: Epidemiology and pathogenesis

被引:347
作者
Goss, Christopher H.
Burns, Jane L.
机构
[1] Univ Washington, Dept Med, Med Ctr, Seattle, WA 98195 USA
[2] Univ Washington, Sch Med, Dept Pediat, Seattle, WA 98195 USA
关键词
D O I
10.1136/thx.2006.060889
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
With the improving survival of patients with cystic fibrosis (CF), the clinical spectrum of this complex multisystem disease continues to evolve. One of the most important clinical events for patients with CF in the course of this disease is an acute pulmonary exacerbation. Clinical and microbial epidemiology studies of CF pulmonary exacerbations continue to provide important insight into the course, prognosis and complications of the disease. This review provides a summary of the pathophysiology, clinical epidemiology and microbial epidemiology of a CF pulmonary exacerbation.
引用
收藏
页码:360 / 367
页数:8
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