Recent advances in defining the hematopoietic stem cell niche

被引：42

作者：

Moore, KA ^{[1
]}

机构：

[1] Princeton Univ, Dept Biol Mol, Lewis Thomas Lab 217, Princeton, NJ 08544 USA

来源：

CURRENT OPINION IN HEMATOLOGY | 2004年 / 11卷 / 02期

关键词：

stem cell niche; microenvironment; stromal cell lines; morphogens; signaling pathways;

D O I：

10.1097/01.moh.0000133652.06863.47

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This review highlights the recent advances made toward elucidating the cellular and molecular attributes of the hematopoietic stem cell niche. Complete knowledge of the cellular architecture and molecular mechanisms in stem cell niches is essential to understanding the basic stem cell behaviors of self-renewal and differentiation.

引用

页码：107 / 111

页数：5

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