Prestimulus oscillations enhance psychophysical performance in humans

被引:302
作者
Linkenkaer-Hansen, K
Nikulin, VV
Palva, S
Ilmoniemi, RJ
Palva, JM
机构
[1] Netherlands Inst Brain Res, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Helsinki, Cent Hosp, Biomag Lab, Ctr Engn, FIN-00029 Helsinki, Finland
[3] Univ Helsinki, Dept Biol & Environm Sci, FIN-00014 Helsinki, Finland
[4] Univ Helsinki, Dept Psychol, Cognit Brain Res Unit, FIN-00014 Helsinki, Finland
[5] Helsinki Brain Res Ctr, FIN-00014 Helsinki, Finland
[6] Karolinska Hosp R2 01, Dept Clin Neurophysiol, Karolinska Inst, SE-17176 Stockholm, Sweden
关键词
ongoing oscillations; prestimulus states; conscious perception; intrinsic stochastic resonance; magnetoencephalography; human;
D O I
10.1523/JNEUROSCI.2584-04.2004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The presence of various ongoing oscillations in the brain is correlated with behavioral states such as restful wakefulness or drowsiness. However, even when subjects aim to maintain a high level of vigilance, ongoing oscillations exhibit large amplitude variability on time scales of hundreds of milliseconds to seconds, suggesting that the functional state of local cortical networks is continuously changing. How this volatility of ongoing oscillations influences the perception of sensory stimuli has remained essentially unknown. We investigated the relationship between prestimulus neuronal oscillations and the subjects' ability to consciously perceive and react to somatosensory stimuli near the threshold of detection. We show that, for prestimulus oscillations at -10, 20, and 40 Hz detected over the sensorimotor cortex, intermediate amplitudes were associated with the highest probability of conscious detection and the shortest reaction times. In contrast, for 10 and 20 Hz prestimulus oscillations detected over the parietal region, the largest amplitudes were associated with the best performance. Our data indicate that the prestimulus oscillatory activity detected over sensorimotor and parietal cortices has a profound effect on the processing of weak stimuli. Furthermore, the results suggest that ongoing oscillations in sensory cortices may optimize the processing of sensory stimuli with the same mechanism as noise sources in intrinsic stochastic resonance.
引用
收藏
页码:10186 / 10190
页数:5
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