Management of bleeding and emergency invasive procedures in patients on dabigatran: Updated guidelines from the French Working Group on Perioperative Haemostasis (GIHP) - September 2016

被引：39

作者：

Albaladejo, Pierre ^{[1
]}

Pernod, Gilles ^{[2
]}

Godier, Anne ^{[3
]}

de Maistre, Emmanuel ^{[4
]}

Rosencher, Nadia ^{[5
]}

Mas, Jean Louis ^{[6
]}

Fontana, Pierre ^{[7
]}

Samama, Charles Marc ^{[5
]}

Steib, Annick ^{[8
]}

Schlumberger, Sylvie ^{[9
]}

Marret, Emmanuel ^{[10
]}

Roullet, Stephanie ^{[11
]}

Susen, Sophie ^{[12
]}

Madi-Jebara, Samia ^{[13
]}

Nguyen, Philippe ^{[14
]}

Schved, Jean Francois ^{[15
]}

Bonhomme, Fanny ^{[16
]}

Sie, Pierre ^{[17
]}

机构：

[1] Grenoble Alpes Univ Hosp, Dept Anaesthesiol & Crit Care, CNRS TIMC IMAG UMR Themas 5525, F-38000 Grenoble, France

[2] Grenoble Alpes Univ, Dept Vasc Med, CNRS TIMC IMAG UMR Themas 5525, Grenoble Alpes Univ Hosp, F-38000 Grenoble, France

[3] Fdn Adolphe de Rothschild, Dept Anaesthesia & Intens Care, F-75019 Paris, France

[4] Dijon Univ Hosp, Dept Biol & Haematol, F-21000 Dijon, France

[5] Paris Descartes Univ, Cochin Univ Hosp, AP HP, Dept Anaesthesia & Intens Care Med, F-75014 Paris, France

[6] Paris Descartes Univ, Dept Neurol, St Anne Hosp, Inserm U894,DHU Neurovasc Sorbonne Paris Cite, F-75014 Paris, France

[7] Univ Hosp Geneva, Div Angiol & Haemostasis, Geneva, Switzerland

[8] Univ Hosp, Dept Anaesthesiol & Intens Care, F-67200 Strasbourg, France

[9] Foch Hosp, Dept Anaesthesiol, F-92150 Suresnes, France

[10] Francobritish Hosp, F-92300 Levallois Perret, France

[11] Univ Hosp, Haut Leveque Hosp, Dept Anaesthesiol & Crit Care 2, F-33000 Bordeaux, France

[12] Reg Hosp, Biol & Pathol Ctr, F-59000 Lille, France

[13] Hotel Dieu de France Hosp, Beirut, Lebanon

[14] Reims Champagne Ardenne Univ, CHU Robert Debre, EA 3801, Dept Haematol,Fac Med,IFR 53,Interact Cellules Mi, F-51100 Reims, France

[15] Montpellier Univ Hosp, St Eloi Hosp, Dept Haematol, F-34000 Montpellier, France

[16] Univ Hosp Geneva, Div Anaesthesiol, Geneva, Switzerland

[17] Toulouse Univ Hosp, Dept Haematol, F-31300 Toulouse, France

来源：

ANAESTHESIA CRITICAL CARE & PAIN MEDICINE | 2018年 / 37卷 / 04期

关键词：

Dabigatran; Emergency; Dabigatran concentration; Antidote; Bleeding; Surgery; ACTIVATED FACTOR-VII; PROTHROMBIN COMPLEX CONCENTRATE; DIRECT ORAL ANTICOAGULANTS; NONVALVULAR ATRIAL-FIBRILLATION; ACUTE INTRACEREBRAL HEMORRHAGE; DRESDEN NOAC REGISTRY; VITAMIN-K-ANTAGONIST; FACTOR-XA INHIBITORS; LONG-TERM TREATMENT; INTRACRANIAL HEMORRHAGE;

D O I：

10.1016/j.accpm.2018.04.009

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

In 2013, the GIHP published guidelines for the management of severe haemorrhages and emergency surgery. This update applies to patients treated with dabigatran, with a bleeding complication or undergoing an urgent invasive procedure. It includes how to handle the available specific antidote (idarucizumab), when to measure dabigatran plasmatic concentration and when to use non-specific measures in these situations. It also includes guidelines on how to perform regional anaesthesia and analgesia procedures. (C) 2018 The Authors. Published by Elsevier Masson SAS on behalf of Societe francaise d'anesthesie et de reanimation (Sfar).

引用

页码：391 / 399

页数：9

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