Fibroblast growth factor signaling during early vertebrate development

被引：435

作者：

Böttcher, RT ^{[1
]}

Niehrs, C ^{[1
]}

机构：

[1] Deutsch Krebsforschungszentrum, Dept Mol Embryol, D-69120 Heidelberg, Germany

来源：

ENDOCRINE REVIEWS | 2005年 / 26卷 / 01期

关键词：

D O I：

10.1210/er.2003-0040

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Fibroblast growth factors (FGFs) have been implicated in diverse cellular processes including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and proliferation. This review presents our current understanding on the roles of FGF signaling, the pathways employed, and its regulation. We focus on FGF signaling during early embryonic processes in vertebrates, such as induction and patterning of the three germ layers as well as its function in the control of morphogenetic movements.

引用

页码：63 / 77

页数：15

共 226 条

[1] Docking protein SNT1 is a critical mediator of fibroblast growth factor signaling during Xenopus embryonic development
Akagi, K
Park, EK
Mood, K
Daar, IO
[J]. DEVELOPMENTAL DYNAMICS, 2002, 223 (02) : 216 - 228
[2] Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly
Allen, BL
Rapraeger, AC
[J]. JOURNAL OF CELL BIOLOGY, 2003, 163 (03) : 637 - 648
[3] Neural induction in whole chick embryo cultures by FGF
Alvarez, IS
Araujo, M
Nieto, MA
[J]. DEVELOPMENTAL BIOLOGY, 1998, 199 (01) : 42 - 54
[4] EXPRESSION OF A DOMINANT NEGATIVE MUTANT OF THE FGF RECEPTOR DISRUPTS MESODERM FORMATION IN XENOPUS EMBRYOS
AMAYA, E
MUSCI, TJ
KIRSCHNER, MW
[J]. CELL, 1991, 66 (02) : 257 - 270
[5] Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
Arman, E
Haffner-Krausz, R
Chen, Y
Heath, JK
Lonai, P
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (09) : 5082 - 5087
[6] PITUITARY EXTRACTS AND STEROID-HORMONES IN CONTROL 3T3-CELL GROWTH
ARMELIN, HA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (09) : 2702 - 2706
[7] A NOVEL FORM OF FGF RECEPTOR-3 USING AN ALTERNATIVE EXON IN THE IMMUNOGLOBULIN DOMAIN-III
AVIVI, A
YAYON, A
GIVOL, D
[J]. FEBS LETTERS, 1993, 330 (03): : 249 - 252
[8] Barnett MW, 1998, DEV GROWTH DIFFER, V40, P47
[9] CONTROL OF VERTEBRATE GASTRULATION - INDUCING SIGNALS AND RESPONDING GENES
BEDDINGTON, RSP
SMITH, JC
[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1993, 3 (04) : 655 - 661
[10] Bel-Vialar S, 2002, DEVELOPMENT, V129, P5103

← 1 2 3 4 5 6 7 8 9 10 →