A new sulfonamide resistance gene (sul3) in Escherichia coli is widespread in the pig population of Switzerland

被引:261
作者
Perreten, V [1 ]
Boerlin, P [1 ]
机构
[1] Univ Bern, Inst Vet Bacteriol, CH-3012 Bern, Switzerland
关键词
D O I
10.1128/AAC.47.3.1169-1172.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A new gene, sul3, which specifies a 263-amino-acid protein similar to a dihydropteroate synthase encoded by the 54-kb conjugative plasmid pVP440 from Escherichia coli was characterized. Expression of the cloned sul3 gene conferred resistance to sulfamethoxazole on E. coli. Two copies of the insertion element IS15Delta/26 flanked the region containing sul3. The sul3 gene was detected in one-third of the sulfonamide-resistant pathogenic E. coli isolates from pigs in Switzerland.
引用
收藏
页码:1169 / 1172
页数:4
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