Physical activity and mortality in older men with diagnosed coronary heart disease

被引:206
作者
Wannamethee, SG [1 ]
Shaper, AG [1 ]
Walker, M [1 ]
机构
[1] UCL Royal Free & Univ Coll Med Sch, Dept Primary Care & Populat Sci, London NW3 2PF, England
关键词
exercise; coronary disease; mortality;
D O I
10.1161/01.CIR.102.12.1358
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background-We have studied the relations between physical activity, types of physical activity, and changes in physical activity and all-cause mortality in men with established coronary heart disease (CHD). Methods and Results-In 1992. 12 to 14 years after the initial screening (Q1) of 7735 men 40 to 59 years of age from general practices in 24 British towns, 5934 (91% of available survivors, mean age 63 years) provided Further information on physical activity (Q92) and were followed up for 5 years; 963 had a physician's diagnosis of CHD (myocardial infarction or angina). After exclusions, there were 772 men with established CHD, 131 of whom died of all causes. The lowest risks for all-cause and cardiovascular mortality were seen in light and moderate activity groups (adjusted relative risk compared with inactive/occasionally active: light, 0.42 (0.25, 0.71); moderate, 0.47 (0.24, 0.92); and moderately vigorous/vigorous, 0.63 (0.39, 1.03). Recreational activity of greater than or equal to 4 hours per weekend, moderate or heavy gardening, and regular walking (>40 min/d) were all associated with a significant reduction in all-cause mortality. Nonsporting activity was more beneficial than sporting activities. Men sedentary at Q1 who began at least light activity by Q92 showed lower mortality rates on follow-up than those who remained sedentary ( relative risk 0.58, 95% CI 0.33 to 1.03; P=0.06). Conclusions-Light or moderate activity in men with established CHD is associated with a significantly lower risk of all-cause mortality. Regular walking and moderate or heavy gardening were sufficient to achieve this benefit.
引用
收藏
页码:1358 / 1363
页数:6
相关论文
共 26 条
[1]   A METAANALYSIS OF PHYSICAL-ACTIVITY IN THE PREVENTION OF CORONARY HEART-DISEASE [J].
BERLIN, JA ;
COLDITZ, GA .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1990, 132 (04) :612-628
[2]  
BETHELL HJN, 1990, BRIT HEART J, V64, P370
[3]   USING THE WHO (ROSE) ANGINA QUESTIONNAIRE IN CARDIOVASCULAR EPIDEMIOLOGY [J].
COOK, DG ;
SHAPER, AG ;
MACFARLANE, PW .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 1989, 18 (03) :607-613
[4]  
COX DR, 1972, J R STAT SOC B, V34, P187
[5]   Evidence-based, cost-effective risk stratification and management after myocardial infarction [J].
Deedwania, PC ;
Amsterdam, EA ;
Vagelos, RH ;
Gregoratos, G ;
Kappagoda, T ;
Viejo, A ;
Caso, R ;
Chatterjee, K ;
Dennish, G ;
Elkayam, U ;
Fonarow, G ;
Golden, P ;
Goldschlager, N ;
Kane, JP ;
Karliner, JS ;
Kloner, RM ;
Shabatei, R ;
Berman, D ;
Superko, B .
ARCHIVES OF INTERNAL MEDICINE, 1997, 157 (03) :273-280
[6]  
*EUR SOC CARD, 1992, EUR HEART J SUPPL, V13, P3
[7]   Effects of walking on coronary heart disease in elderly men - The Honolulu Heart Program [J].
Hakim, AA ;
Curb, JD ;
Petrovitch, H ;
Rodriguez, BL ;
Yano, K ;
Ross, GW ;
White, LR ;
Abbott, RD .
CIRCULATION, 1999, 100 (01) :9-13
[8]  
HASKELL WL, 1994, MED SCI SPORT EXER, V26, P815
[9]  
KALLIO V, 1979, LANCET, V2, P1081
[10]   PROGNOSTIC-SIGNIFICANCE OF DAILY PHYSICAL-ACTIVITY AFTER 1ST ACUTE MYOCARDIAL-INFARCTION [J].
KITAJIMA, K ;
SASAKI, J ;
KONO, S ;
ARAKAWA, K .
AMERICAN HEART JOURNAL, 1990, 119 (05) :1193-1194