Toll signaling: the enigma variations

被引：47

作者：

Wasserman, SA ^{[1
]}

机构：

[1] Univ Calif San Diego, Ctr Mol Genet, Div Biol, La Jolla, CA 92093 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2000年 / 10卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(00)00118-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Experiments reported in the past year have revealed considerable diversity in Toll-mediated pathways for signal transduction in development and innate immunity. Rather than function as a well conserved signaling cassette, Toll receptors and associated factors have apparently evolved as a diverse set of configurations to defend against microbial infection in species ranging from plants to humans.

引用

页码：497 / 502

页数：6

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