Detection of circulating Aspergillus fumigatus galactomannan:: Value and limits of the Platelia test for diagnosing invasive aspergillosis

被引：107

作者：

Pinel, C ^{[1
]}

Fricker-Hidalgo, H

Lebeau, B

Garban, F

Hamidfar, R

Ambroise-Thomas, P

Grillot, R

机构：

[1] CHU Grenoble, Serv Parasitol Mycol, F-38043 Grenoble, France

[2] CHU Grenoble, Dept Cancerol, F-38043 Grenoble, France

[3] CHU Grenoble, Dept Med Aigue Specialisee, F-38043 Grenoble, France

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 05期

关键词：

D O I：

10.1128/JCM.41.5.2184-2186.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The effectiveness of galactomannan detection with the Platelia test was evaluated in a prospective study of 3,327 sera from 807 patients. The specificity was 99.6% (748 of 751 cases). For the groups of patients with proven and probable invasive aspergillosis, the sensitivity was 50.0% (17 of 34 cases). The disappointing sensitivity associated with the presence of rare false-positive cases underlines the limits of this test.

引用

页码：2184 / 2186

页数：3

共 20 条

[1] Andriole VT, 1996, INFECT AGENT DIS, V5, P47
[2] Detection of Aspergillus galactomannan antigen in foods and antibiotics
Ansorg, R
van den Boom, R
Rath, PM
[J]. MYCOSES, 1997, 40 (9-10) : 353 - 357
[3] Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus
Ascioglu, S
Rex, JH
de Pauw, B
Bennett, JE
Bille, J
Crokaert, F
Denning, DW
Donnelly, JP
Edwards, JE
Erjavec, Z
Fiere, D
Lortholary, O
Maertens, J
Meis, JF
Patterson, TF
Ritter, J
Selleslag, D
Shah, PM
Stevens, DA
Walsh, TJ
[J]. CLINICAL INFECTIOUS DISEASES, 2002, 34 (01) : 7 - 14
[4] Invasive aspergillosis in allogeneic stem cell transplant recipients: Increasing antigenemia is associated with progressive disease
Boutboul, F
Alberti, C
Leblanc, T
Sulahian, A
Gluckman, E
Derouin, F
Ribaud, P
[J]. CLINICAL INFECTIOUS DISEASES, 2002, 34 (07) : 939 - 943
[5] Invasive aspergillosis
Denning, DW
[J]. CLINICAL INFECTIOUS DISEASES, 1998, 26 (04) : 781 - 803
[6] Transient aspergillus antigenaemia: think of milk
Gangneux, JP
Lavarde, D
Bretagne, S
Guiguen, C
Gandemer, V
[J]. LANCET, 2002, 359 (9313) : 1251 - 1251
[7] Value of antigen and antibody detection, and blood evaluation parameters in diagnosis of avian invasive aspergillosis
Graczyk T.K.
Cranfield M.R.
Klein P.N.
[J]. Mycopathologia, 1997, 140 (3) : 121 - 127
[8] Aspergillus galactomannan detection in the diagnosis of invasive aspergillosis in cancer patients
Herbrecht, R
Letscher-Bru, V
Oprea, C
Lioure, B
Waller, J
Campos, F
Villard, O
Liu, KL
Natarajan-Amé, S
Lutz, P
Dufour, P
Bergerat, JP
Candolfi, E
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (07) : 1898 - 1906
[9] Invasive fungal infections in pediatric bone marrow transplant recipients: single center experience of 10 years
Hovi, L
Saarinen-Pihkala, UM
Vettenranta, K
Saxen, H
[J]. BONE MARROW TRANSPLANTATION, 2000, 26 (09) : 999 - 1004
[10] Comparison of commercial latex agglutination and sandwich enzyme immunoassays with a competitive binding inhibition enzyme immunoassay for detection of antigenemia and antigenuria in a rabbit model of invasive aspergillosis
Hurst, SF
Reyes, GH
McLaughlin, DW
Reiss, E
Morrison, CJ
[J]. CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2000, 7 (03) : 477 - 485

← 1 2 →