Nematicidal resorcylides from the aquatic fungus Caryospora callicarpa YMF1.01026

被引：50

作者：

Dong, Jinyan

Zhu, Yanhui

Song, Hongchuan

Li, Ru

He, Hongping

Liu, Haiyang

Huang, Rong

Zhou, Yongping

Wang, Le

Cao, Yi

Zhang, Keqin ^{[1
]}

机构：

[1] Yunnan Univ, Key Lab Conservat & Utilizat Bioresources, Kunming 650091, Yunnan, Peoples R China

[2] Yunnan Normal Univ, Provincial Key Lab Rural Energy Engn, Kunming 650092, Peoples R China

[3] Chinese Acad Sci, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China

来源：

JOURNAL OF CHEMICAL ECOLOGY | 2007年 / 33卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Caryospora carllicarpa; freshwater fungi; nematicidal; resorcylide;

D O I：

10.1007/s10886-007-9256-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This study investigated metabolites with activities against plant parasite nematodes from the fresh-water fungus Caryospora callicarpa YMF 1.01026. We obtained three novel tetradecalactone metabolites, caryospomycins A-C, with such activities. The chemical structures of these were determined through NMR spectroscopic analysis and were found to belong to the 14-membered macrolides with a fused 1,2-dimethoxy4-hydroxybenzene ring, a rare structure among the resorcylides. In the in vitro tests, all three compounds exhibited moderate killing activity against the nematode Bursaphelenchus xylophilus. To our knowledge, this is the first report of secondary metabolites in the aquatic fungal genus Caryospora.

引用

页码：1115 / 1126

页数：12

共 55 条

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