Ciprofloxacin resistance in Neisseria gonorrhoeae in England and Wales in 2002

被引：76

作者：

Fenton, KA

Ison, C

Johnson, AP

Rudd, E

Soltani, M

Martin, I

Nichols, T

Livermore, DM

机构：

[1] Hlth Protect Agcy, HIV STI Div, Ctr Communicable Dis Surveillance, London NW9 5EQ, England

[2] Hlth Protect Agcy, Cent Publ Hlth Lab, London NW9 5EQ, England

[3] UCL Royal Free & UCL Med Sch, Ctr Infect Dis Epidemiol, Dept Primary Care, London, England

[4] UCL Royal Free & UCL Med Sch, Ctr Infect Dis Epidemiol, Dept Populat Sci, London, England

[5] UCL Royal Free & UCL Med Sch, Ctr Infect Dis Epidemiol, Dept Sexually Transmitted Dis, London, England

[6] Univ London Imperial Coll Sci Technol & Med, Dept Infect Dis & Microbiol, London, England

来源：

LANCET | 2003年 / 361卷 / 9372期

关键词：

D O I：

10.1016/S0140-6736(03)13489-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) monitors trends in antimicrobial resistance in consecutive gonococcal isolates from 26 genitourinary medicine clinics in England and Wales. In 2002, 2204 gonococcal isolates were tested, and the overall prevalence of ciprofloxacin resistance (minimum Inhibitory concentration greater than or equal to1 mg/L) was 9.8%, compared with 3.1% in 2001 and 2.1% in 2000. Between 2001 and 2002, prevalence of ciprofloxacin resistance increased two to three-fold, irrespective of recent sexual contact overseas, sex, or residence within or outside of London. These findings suggest that national and local treatment guidelines need to be reviewed urgently.

引用

页码：1867 / 1869

页数：3

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