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Engineering and material considerations in islet cell transplantation

被引：42
作者：
Chaikof, EL [1 ]
机构：
[1] Emory Univ, Sch Med, Dept Surg, Atlanta, GA 30322 USA
[2] Georgia Inst Technol, Sch Chem Engn, Atlanta, GA 30322 USA
来源：
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING | 1999年 / 1卷
关键词：
diabetes; biomaterials; artificial organs; immunoisolation; semipermeable membranes;
D O I：
10.1146/annurev.bioeng.1.1.103
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The successful application and optimization of cell transplantation will require quantitative engineering design and analysis of cells and materials in which relevant biological processes remain complex and incompletely defined. This report primarily reviews the engineering and material considerations in islet cell transplantation, including established biological constraints and biohybrid devices for cell delivery, as well as available barrier materials and the associated processing strategies directed at the control of solute transport, barrier permeability, and host responses at the biological-material interface. Also described are current areas of investigation with particular promise as enabling technologies for accelerating the clinical effectiveness of islet cell transplantation.
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收藏
页码：103 / 127
页数：25
相关论文
共 103 条
  • [1] Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients
    Aebischer, P
    Schluep, M
    Deglon, N
    Joseph, JM
    Hirt, L
    Heyd, B
    Goddard, M
    Hammang, JP
    Zurn, AD
    Kato, AC
    Regli, F
    Baetge, EE
    [J]. NATURE MEDICINE, 1996, 2 (06) : 696 - 699
  • [2] TRANSPLANTATION IN HUMANS OF ENCAPSULATED XENOGENEIC CELLS WITHOUT IMMUNOSUPPRESSION - A PRELIMINARY-REPORT
    AEBISCHER, P
    BUCHSER, E
    JOSEPH, JM
    FAVRE, J
    DETRIBOLET, N
    LYSAGHT, M
    RUDNICK, S
    GODDARD, M
    [J]. TRANSPLANTATION, 1994, 58 (11) : 1275 - 1277
  • [3] AGIRE GH, 1954, JNCI-J NATL CANCER I, V15, P493
  • [4] Long-term function (6 years) of islet allografts in type 1 diabetes
    Alejandro, R
    Lehmann, R
    Ricordi, C
    Kenyon, NS
    Angelico, MC
    Burke, G
    Esquenazi, V
    Nery, J
    Betancourt, AE
    Kong, SS
    Miller, J
    Mintz, DH
    [J]. DIABETES, 1997, 46 (12) : 1983 - 1989
  • [5] Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts
    Allison, J
    Georgiou, HM
    Strasser, A
    Vaux, DL
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (08) : 3943 - 3947
  • [6] Avgoustiniatos ES, 1997, ANN NY ACAD SCI, V831, P145
  • [7] Baker R. W., 1991, MEMBRANE SEPARATION
  • [8] A ROLE FOR CD95 LIGAND IN PREVENTING GRAFT-REJECTION
    BELLGRAU, D
    GOLD, D
    SELAWRY, H
    MOORE, J
    FRANZUSOFF, A
    DUKE, RC
    [J]. NATURE, 1995, 377 (6550) : 630 - 632
  • [9] NEOVASCULARIZATION OF SYNTHETIC MEMBRANES DIRECTED BY MEMBRANE MICROARCHITECTURE
    BRAUKER, JH
    CARRBRENDEL, VE
    MARTINSON, LA
    CRUDELE, J
    JOHNSTON, WD
    JOHNSON, RC
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1995, 29 (12): : 1517 - 1524
  • [10] Brissová M, 1998, J BIOMED MATER RES, V39, P61, DOI 10.1002/(SICI)1097-4636(199801)39:1<61::AID-JBM8>3.0.CO
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