New stable reagents for the nucleophilic trifluoromethylation.: 1.: Trifluoromethylation of carbonyl compounds with N-formylmorpholine derivatives

被引：105

作者：

Billard, T ^{[1
]}

Bruns, S ^{[1
]}

Langlois, BR ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, UMR 5622, SERCOF, F-69622 Villeurbanne, France

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 14期

关键词：

D O I：

10.1021/ol005987o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new stable equivalent of the trifluoromethyl anion has been synthesized from fluoroform, It reacts with nonenolizable carbonyl compounds such as the Ruppert's reagent.

引用

页码：2101 / 2103

页数：3

共 15 条

[1] Banks R.E., 1994, ORGANOFLUORINE CHEM
[2] Filler R., 1993, ORGANOFLUORINE COMPO
[3] Fluoroform:: An efficient precursor for the trifluoromethylation of aldehydes
Folléas, B
Marek, I
Normant, JF
Saint Jalmes, L
[J]. TETRAHEDRON LETTERS, 1998, 39 (19) : 2973 - 2976
[4] Fluoroform:: an efficient precursor for the trifluoromethylation of aldehydes
Folléas, B
Marek, I
Normant, JF
Saint-Jalmes, L
[J]. TETRAHEDRON, 2000, 56 (02) : 275 - 283
[5] Gross U., 1999, ORGANOFLUORINE COM A, VE10a, P18
[6] HUDLICKY M, 1995, ACS MONOGRAPH, V187
[7] LARGE S, IN PRESS J ORG CHEM
[8] Maggiarosa N, 1999, ANGEW CHEM INT EDIT, V38, P2252, DOI 10.1002/(SICI)1521-3773(19990802)38:15<2252::AID-ANIE2252>3.0.CO
[9] 2-Z
[10] TRIFLUOROMETHYLATIONS AND RELATED REACTIONS IN ORGANIC-CHEMISTRY
MCCLINTON, MA
MCCLINTON, DA
[J]. TETRAHEDRON, 1992, 48 (32) : 6555 - 6666

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