Antibiotic resistance of E-coli in sewage and sludge

被引：392

作者：

Reinthaler, FF ^{[1
]}

Posch, J ^{[1
]}

Feierl, G ^{[1
]}

Wüst, G ^{[1
]}

Haas, D ^{[1
]}

Ruckenbauer, G ^{[1
]}

Mascher, F ^{[1
]}

Marth, E ^{[1
]}

机构：

[1] Graz Univ, Inst Hyg, A-8010 Graz, Austria

来源：

WATER RESEARCH | 2003年 / 37卷 / 08期

关键词：

antibiotics; resistance; sewage; sludge; receiving water; E; coli;

D O I：

10.1016/S0043-1354(02)00569-9

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The aim of the study is the evaluation of resistance patterns of E. coli in wastewater treatment plants without an evaluation of basic antibiotic resistance mechanisms. Investigations have been done in sewage, sludge and receiving waters from three different sewage treatment plants in southern Austria. A total of 767 E coli isolates were tested regarding their resistance to 24 different antibiotics. The highest resistance rates were found in E coli strains of a sewage treatment plant which treats not only municipal sewage but also sewage from a hospital. Among the antimicrobial agents tested, the highest resistance rates in the penicillin group were found for Ampicillin (AM) (up to 18%) and Piperacillin (PIP) (up to 12%); in the cephalosporin group for Cefalothin (CF) (up to 35%) and Cefuroxime-Axetil (CXMAX) (up to 11%); in the group of quinolones for Nalidixic acid (NA) (up to 15%); and for Trimethoprime/Sulfamethoxazole (SXT) (up to 13%) and for Tetracycline (TE) (57%). Median values for E. coli in the inflow (crude sewage) of the plants were between 2.0 x 10(4) and 6.1 x 10(4) CFU/ml (Coli ID-agar, BioMerieux 42017) but showed a 200-fold reduction in all three plants in the effluent. Nevertheless, more than 10(2) CFU E. coli/ml reached the receiving water and thus sewage treatment processes contribute to the dissemination of resistant bacteria in the environment. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1685 / 1690

页数：6

共 23 条

[1] INSITU STUDIES WITH MEMBRANE-DIFFUSION CHAMBERS OF ANTIBIOTIC-RESISTANCE TRANSFER IN ESCHERICHIA-COLI [J].