Cloning and chromosomal localization of a novel gene-encoding a human beta(2)-integrin alpha subunit

被引:15
作者
Wong, DA
Davis, EM
LeBeau, M
Springer, TA
机构
[1] HARVARD UNIV,SCH MED,CTR BLOOD RES,BOSTON,MA 02115
[2] UNIV CHICAGO,DEPT MED,CHICAGO,IL 60637
关键词
recombinant DNA; polymerase chain reaction; ITGAD; sequence homology;
D O I
10.1016/0378-1119(95)00869-1
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
We isolated a partial genomic clone encoding ITGAD, a novel beta(2)-integrin alpha subunit. The ITGAD gene is highly homologous to the three previously known alpha subunit-encoding genes, that compose the beta(2) integrin family, in deduced amino acid sequence, intron/exon structure and mapping location (chromosome 16p11).
引用
收藏
页码:291 / 294
页数:4
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