Roles of prolactin and gonadotropin-releasing hormone in rheumatic diseases

被引：63

作者：

Walker, SE

Jacobson, JD

机构：

[1] Harry S Truman Mem Vet Hosp, Columbia, MO 65201 USA

[2] Univ Missouri, Dept Internal Med, Columbia, MO USA

[3] Univ Missouri, Sch Med, Sect Endocrinol Diabet, Kansas City, MO 64110 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2000年 / 26卷 / 04期

关键词：

D O I：

10.1016/S0889-857X(05)70166-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Prolactin, a peptide hormone, is produced by lactotrophs in the anterior pituitary gland and stimulates mammary growth and differentiation. Pituitary secretion of prolactin is stimulated by suckling and stress and is restricted by hypothalamic dopamine. It is recognized that prolactin is produced in a number of sites outside the pituitary, including the brain and lymphocytes. Prolactin is important in maintaining immune competence and has the potential to play a role in the pathogenesis of autoimmune illnesses.

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页码：713 / +

页数：25

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