Lipid rafts and membrane traffic

被引：252

作者：

Hanzal-Bayer, Michael F. ^{[1
]}

Hancock, John F. ^{[1
]}

机构：

[1] Univ Queensland, Inst Mol Biosci, St Lucia, Qld 4072, Australia

来源：

FEBS LETTERS | 2007年 / 581卷 / 11期

关键词：

rafts; membrane microstructure; cholesterol-facilitated; liquid-ordered;

D O I：

10.1016/j.febslet.2007.03.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Membrane rafts are regions of increased lipid acyl chain order that differ in their lipid and protein composition from the surrounding membrane. By providing an additional level of compartmentalization they have been proposed to serve many functions in cellular signal transduction and trafficking. We will review their potential involvement in different forms of membrane traffic, explicitly excluding signalling, and discuss select aspects of the raft hypothesis in its current form. (C) 2007 Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies.

引用

页码：2098 / 2104

页数：7

共 50 条

[1] Motoring around the Golgi [J].

Allan, VJ ;

Thompson, HM ;

McNiven, MA .

NATURE CELL BIOLOGY, 2002, 4 (10) :E236-E242

[2] Biochemical characterization of detergent-resistant membranes: a systematic approach [J].

Babiychuk, Eduard B. ;

Draeger, Annette .

BIOCHEMICAL JOURNAL, 2006, 397 :407-416

[3] Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes [J].

Bacia, K ;

Schwille, P ;

Kurzchalia, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (09) :3272-3277

[4] Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension [J].

Baumgart, T ;

Hess, ST ;

Webb, WW .

NATURE, 2003, 425 (6960) :821-824

[5] CHOLESTEROL AND THE GOLGI-APPARATUS [J].

BRETSCHER, MS ;

MUNRO, S .

SCIENCE, 1993, 261 (5126) :1280-1281

[6] The HIV lipidome:: A raft with an unusual composition [J].

Brügger, B ;

Glass, B ;

Haberkant, P ;

Leibrecht, I ;

Wieland, FT ;

Kräusslich, HG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (08) :2641-2646

[7] Apical protein transport [J].

Delacour, D. ;

Jacob, R. .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2006, 63 (21) :2491-2505

[8] Timeline - Lipids on the frontier: a century of cell-membrane bilayers [J].

Edidin, M .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2003, 4 (05) :414-418

[9] Lipid rafts mediate chemotropic guidance of nerve growth cones [J].

Guirland, C ;

Suzuki, S ;

Kojima, M ;

Lu, B ;

Zheng, JQ .

NEURON, 2004, 42 (01) :51-62

[10] Lipid rafts: contentious only from simplistic standpoints [J].

Hancock, John F. .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2006, 7 (06) :456-462

← 1 2 3 4 5 →