Fluorescence lifetime imaging with picosecond resolution for biomedical applications

被引：115

作者：

Dowling, K

Dayel, MJ

Lever, MJ

French, PMW

Hares, JD

Dymoke-Bradshaw, AKL

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Phys, London SW7 2BZ, England

[2] Univ London Imperial Coll Sci Technol & Med, Dept Biol & Med Syst, London SW7 2BZ, England

[3] Kentech Instruments Ltd, Unit 9, Hall Farm Workshops, Didcot OX11 9AG, Oxon, England

来源：

OPTICS LETTERS | 1998年 / 23卷 / 10期

关键词：

D O I：

10.1364/OL.23.000810

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We describe a novel whole-field fluorescence lifetime imaging system, based on a time-gated image intensifier and a solid-state laser oscillator-amplifier, that images lifetime differences of less than 10 ps. This system was successfully applied to discrimination between biological tissue constituents. (C) 1998 Optical Society of America.

引用

收藏

页码：810 / 812

页数：3

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