Epidemiology, pathophysiology and treatment of pathological gambling

被引:34
作者
Blanco, C
Ibáñez, A
Sáiz-Ruiz, J
Blanco-Jerez, C
Nunes, EV
机构
[1] Columbia Univ, New York State Psychiat Inst, Dept Psychiat, New York, NY 10032 USA
[2] Univ Alcala de Henares, Hosp Ramon y Cajal, Dept Psychiat, Madrid, Spain
[3] Univ Alcala de Henares, Hosp Ramon y Cajal, Dept Biochem Res, Madrid, Spain
关键词
D O I
10.2165/00023210-200013060-00002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Pathological gambling is a prevalent disorder that is gaining attention from patients, clinicians and policy makers. Aetiological factors that have been related to pathological gambling include: (i) abnormalities in the serotonergic, dopaminergic and noradrenergic systems; (ii) cognitive distortions; and (iii) a reinforcement of the gambling activity by either episodic gains or the excitement that accompanies gambling. Male gender, urban residence, lower income and the presence of a comorbid psychiatric disorder (particularly substance abuse) appear to constitute risk factors for the presence of the disorder. A number of treatments have been suggested as potentially effective: Gamblers Anonymous, behavioural therapy, manualised cognitive therapy and several medications. At present, only manualised cognitive therapy and the selective serotonin (5-hvdroxytryptamine: 5-HT) reuptake inhibitor flwuvoxamine have shown efficacy in systematic (albeit small) studies. However, much research remains to be done to better understand the psychophysiology of pathological gambling, to firmly demonstrate the efficacy of the different proposed treatment approaches, and to establish criteria for treatment selection fur individual patients.
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收藏
页码:397 / 407
页数:11
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