Treatment outcomes stratified by baseline immunological status among young children receiving nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in resource-limited settings

被引：33

作者：

O'Brien, Daniel P.

Sauvageot, Delphine

Olson, David

Schaeffer, Myrto

Humblet, Pierre

Pudjades, Mar

Ellman, Tom

Zachariah, Rony

Szumilin, Elisabeth

Arnould, Line

Read, Tony

机构：

[1] Med San Frontieres, AIDs Working Grp, NL-1001 EA Amsterdam, Netherlands

[2] Epictr, Paris, France

[3] Med San Frontieres, Brussels Operat Ctr, NL-1001 EA Amsterdam, Netherlands

来源：

CLINICAL INFECTIOUS DISEASES | 2007年 / 44卷 / 09期

关键词：

D O I：

10.1086/513433

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A study of 568 children aged < 5 years who commenced non-nucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in resource-limited settings revealed good early outcomes. After 12 months of antiretroviral therapy, survival probability was 0.89 ( 95% confidence interval, 0.86 - 0.92), with no significant difference among children stratified on the basis of baseline immunological levels; 62% attained a CD4 cell percentage > 25%, and 7% continued to have a CD4 cell percentage < 15%.

引用

收藏

页码：1245 / 1248

页数：4

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