In vitro activities of OPT-80 and comparator drugs against intestinal bacteria

被引：107

作者：

Finegold, SA

Molitoris, D

Vaisanen, ML

Song, YL

Liu, CX

Bolaños, M

机构：

[1] VA Greater Los Angeles Healthcare Syst, Med Serv, Los Angeles, CA USA

[2] VA Greater Los Angeles Healthcare Syst, Res Serv, Los Angeles, CA USA

[3] Univ Calif Los Angeles, Sch Med, Dept Med, Los Angeles, CA 90024 USA

[4] Univ Calif Los Angeles, Sch Med, Dept Microbiol Mol Genet & Immunol, Los Angeles, CA 90024 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 12期

关键词：

D O I：

10.1128/AAC.48.12.4898-4902.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed good activity against most clostridia, staphylococci, and enterococci, but streptococci, aerobic and facultative gram-negative rods, anaerobic gram-negative rods, and Clostridium ramosum were resistant. Poor activity against anaerobic gram-negative rods may maintain colonization resistance.

引用

页码：4898 / 4902

页数：5

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