Dementia in idiopathic Parkinson's syndrome

被引：24

作者：

Fuchs, GA ^{[1
]}

Gemende, I ^{[1
]}

Herting, B ^{[1
]}

Lemke, MR ^{[1
]}

Ehlwein, C ^{[1
]}

Reichmann, H ^{[1
]}

Rieke, J ^{[1
]}

Emmans, D ^{[1
]}

Volkmann, J ^{[1
]}

机构：

[1] Parkinson Clin Wolfach, D-77709 Wolfach, Germany

来源：

JOURNAL OF NEUROLOGY | 2004年 / 251卷 / Suppl 6期

关键词：

dementia; Parkinson's disease; Lewy body dementia; cholinesterase inhibitor;

D O I：

10.1007/s00415-004-1607-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Approximately 25% of patients with idiopathic Parkinson's disease (IPD) later develop dementia, with the typical characteristics as detailed in ICD-10 and DSM-IV Differential diagnosis has to exclude dementia due to Lewy bodies, subcortical vascular encephalopathy and subcortical dementia due to progressive supranuclear paralysis or corticobasal degeneration. Several studies showed promising results for cholinesterase inhibitors such as donepezile, rivastigmine and galantamine. The demented Parkinsonian patients then present with improvement in cognitive function while motor skills do not deteriorate.

引用

页码：28 / 32

页数：5

共 20 条

[1] Cognitive, psychiatric and motor response to galantamine in Parkinson's disease with dementia [J].