Chlorogenic acid from coffee beans: evaluating the evidence for a blood pressure-regulating health claim

被引:38
作者
Loader, Tara B. [1 ,3 ]
Taylor, Carla G. [1 ,2 ,3 ]
Zahradka, Peter [1 ,2 ,3 ]
Jones, Peter J. H. [1 ,4 ,5 ]
机构
[1] Univ Manitoba, Dept Human Nutr Sci, Winnipeg, MB, Canada
[2] Univ Manitoba, Dept Physiol & Pathophysiol, Winnipeg, MB, Canada
[3] St Boniface Gen Hosp, Albrechtsen Res Ctr, Canadian Ctr Agrifood Res Hlth & Med, Winnipeg, MB, Canada
[4] Univ Manitoba, Dept Food Sci, Winnipeg, MB, Canada
[5] Richardson Ctr Funct Foods & Nutraceut, 196 Innovat Dr, Winnipeg, MB R3T 2N2, Canada
关键词
blood pressure; chlorogenic acid; coffee; health claim; hypertension; EDUCATION-PROGRAM RECOMMENDATIONS; HYDROXYHYDROQUINONE-FREE COFFEE; TOTAL PHENOLIC CONTENTS; ENDOTHELIAL FUNCTION; NITRIC-OXIDE; DOSE-RESPONSE; DOUBLE-BLIND; SIMULTANEOUS CONSUMPTION; ANTIOXIDANT CAPACITIES; CANADIAN HYPERTENSION;
D O I
10.1093/nutrit/nuw057
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 [营养与食品卫生学];
摘要
The consumption of coffee has been associated with a number of health benefits, including a reduced risk of cardiovascular disease. Hypertension is an important risk factor for adverse cardiovascular events. Coffee may help reduce blood pressure (BP) in humans, which might be attributable to its polyphenolic compound, chlorogenic acid. The high incidence of hypertension among Canadians underscores the need for new and effective strategies to reduce BP. Dietary interventions may constitute such a strategy, but consumers need to be informed about which foods are most effective for regulating BP. To guide healthy eating, Health Canada permits the use of health claims on the labels of foods that confer health benefits. Currently, there is only one health claim for BP regulation. Additional health claims for foods that assist in BP regulation are therefore warranted. This review provides background information on chlorogenic acid and examines the evidence regarding the use of chlorogenic acid for BP regulation in the context of Health Canada's health claims framework.
引用
收藏
页码:114 / 133
页数:20
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