New synthetic approaches to 2-perfluoroalkyl-4H-pyran-4-ones

被引：28

作者：

Tyvorskii, VI

Bobrov, DN

Kulinkovich, OG

De Kimpe, N

Tehrani, KA

机构：

[1] Belarusian State Univ, Dept Organ Chem, Minsk 220050, BELARUS

[2] Univ Ghent, Fac Agr & Appl Biol Sci, Dept Organ Chem, B-9000 Ghent, Belgium

来源：

TETRAHEDRON | 1998年 / 54卷 / 12期

关键词：

D O I：

10.1016/S0040-4020(98)83018-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient synthesis of 5-substituted 2-perfluoroalkyl-4H-pyran-4-ones by dehydration of 2,3-dihydro-3-hydroxy-6-perfluoroalkyl-4H-pyran-4-ones is described. The 6-substituted and parent 2-perfluoroalkyl-4H-pyran-4-ones have been more successfully prepared using the condensation of alkyl enol ethers, derived from beta-dicarbonyl compounds, with ethyl perfluoroalkanoates. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2819 / 2826

页数：8

共 23 条

[1] AN EXPEDIENT AND HIGH YIELDING SYNTHESIS OF MEFLOQUINE, VIA FLUORIDE ION-CATALYZED WITTIG REARRANGEMENT .1. [J].