Gene regulation: Towards a circuit engineering discipline

被引：71

作者：

McAdams, HH ^{[1
]}

Arkin, A

机构：

[1] Stanford Univ, Med Ctr, Sch Med, Dept Dev Biol, Stanford, CA 94305 USA

[2] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[4] Univ Calif Berkeley, EO Lawrence Berkeley Natl Lab, Phys Biosci Div, Berkeley, CA 94720 USA

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 08期

关键词：

D O I：

10.1016/S0960-9822(00)00440-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Genetic circuits can now be engineered that perform moderately complicated switching functions or exhibit predictable dynamical behavior. These 'forward engineering' techniques may have to be combined with directed evolution techniques to produce robustness comparable with naturally occurring circuits.

引用

页码：R318 / R320

页数：3

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