Comparative study of Scutellaria planipes and Scutellaria baicalensis

Scutellaria planipes, a species of Scutellaria, was explored by comparing to Scutellaria baicalensis, a pharmacopoeia species, Four principle flavonoids in both the plant roots were analyzed by using a reversed-phase chromatographic system with a chemically bonded ODS silica gel column and phosphate buffer:methanol (68:32 and 1:1) as mobile phase. Their contents were similar in both plant roots, Antiallergic and antibacterial activities in vitro and acute toxicity were compared, The results provided valuable data for S. planipes as a potential medicinal resource. (C) 1998 John Wiley & Sons, Ltd.