The first Space-VLBI mission, VSOP, started successfully with the launch of the dedicated space-VLBI satellite HALCA in 1997. The mission has been in scientific operation in the 1.6 GHz and 5 GHz bands, and studies have been done mainly of the jet phenomena related to active galactic nuclei. Observing at higher frequencies has the advantage of less absorption through the ambient plasma and less contribution from scattering, and also has the merit of resulting in higher angular resolution observations. A second generation space-VLBI mission, VSOP-2, has been planned by the working group formed at ISAS/JAXA with many collaborators. The spacecraft is planned to observe in the 8, 22 and 43 GHz bands with cooled receivers for the two higher bands, and with a maximum angular resolution at 43 GHz (7 mm) of about 40 micro-arcseconds. The system design, including the spacecraft and ground facilities, will be introduced, and the impact for sub-mm space-VLBI further into the future will be discussed.