Oriloc: prediction of replication boundaries in unannotated bacterial chromosomes

被引：93

作者：

Frank, AC ^{[1
]}

Lobry, JR ^{[1
]}

机构：

[1] Univ Lyon 1, Lab BBE, CNRS, UMR 5558, F-69622 Villeurbanne, France

来源：

BIOINFORMATICS | 2000年 / 16卷 / 06期

关键词：

D O I：

10.1093/bioinformatics/16.6.560

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A program called Oriloc has been developed for the prediction of bacterial replication origins. The method builds on the fact that there are compositional asymmetries between the leading and the lagging strand for replication. The program works with unannotated sequences in fasta format and therefore uses glimmer 2.0 outputs to discriminate between codon positions so as to increase the signal/noise ratio.

引用

页码：560 / 561

页数：2

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