Molecular identification of a glucose transporter from fish muscle

被引：78

作者：

Planas, JV ^{[1
]}

Capilla, E ^{[1
]}

Gutiérrez, J ^{[1
]}

机构：

[1] Univ Barcelona, Fac Biol, Dept Fisiol, E-08028 Barcelona, Spain

来源：

FEBS LETTERS | 2000年 / 481卷 / 03期

关键词：

glucose transporter; muscle; fish; trout;

D O I：

10.1016/S0014-5793(00)02020-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In mammals and birds, several isoforms of facilitative glucose transporters have been identified (GLUT1-4), but no information is available regarding the molecules involved in glucose transport in other vertebrates, Here,ve report the cloning of a GLUT molecule from fish muscle with high sequence homology to GLUT4 and containing features characteristic of a functional GLUT. Fish GLUT is expressed predominantly in skeletal muscle, kidney and gill, which are tissues with known high glucose utilization. These results indicate that fish GLUT is structurally, and perhaps functionally, similar to the other known GLUTs expressed in muscle in mammalian and avian species. (C) 2000 Federation of European Biochemical Societies, Published by Elsevier Science B.V. All rights reserved.

引用

页码：266 / 270

页数：5

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