Optical characteristics of biological molecules in the Terahertz gap

被引:5
作者
Globus, T [1 ]
Parthasarathy, R [1 ]
Khromova, T [1 ]
Woolard, D [1 ]
Swami, N [1 ]
Gatesman, AJ [1 ]
Waldman, J [1 ]
机构
[1] Univ Virginia, Dept Elect & Comp Engn, Charlottesville, VA 22904 USA
来源
CHEMICAL AND BIOLOGICAL STANDOFF DETECTION II | 2004年 / 5584卷
关键词
terahertz; spectroscopy; transmission; reflection; refractive index; absorption coefficient; dispersion; bio-materials;
D O I
10.1117/12.580838
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Terahertz Spectroscopy has been recently introduced as a promising technique for the collection of signature data in transmission spectra of biological materials including warfare agent simulants. To characterize material rather than sample, it is always desirable to obtain the material's optical properties as functions of frequency. In this work, we present results from parallel measurements of reflection and transmission spectra of biological molecules to enable detailed and direct calculation of refractive index and absorption coefficient spectra in the terahertz gap. DNA samples from herring and salmon as well as samples of Ovalbumin and Bacillus Subtillus spores have been characterized. The technique for simulation is described. Reflection spectra reveal resonance features similar to those demonstrated earlier for transmission, thereby affirming molecular vibrational modes in biological materials. The dispersion of refractive index and absorption coefficient is demonstrated within the Terahertz gap of 10 cm(-1) to 25 cm(-1).
引用
收藏
页码:1 / 10
页数:10
相关论文
共 17 条
[1]  
BRUCHERSEIFER M, 2000, APPL PHYS LETT, V77
[2]   Sub-millimetre wave absorption spectra of artificial RNA molecules [J].
Globus, T ;
Bykhovskaia, M ;
Woolard, D ;
Gelmont, B .
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2003, 36 (11) :1314-1322
[3]  
Globus T., 2003, International Journal of High Speed Electronics and Systems, V13, P903, DOI 10.1142/S0129156403002083
[4]  
GLOBUS T, 2003, TERAHERTZ SENSING TE, V2
[5]  
GLOBUS T, 1999, P SOC PHOTO-OPT INS, V5268, P10
[6]  
Globus T, 2003, INT S SPECTR SENS RE
[7]  
GLOBUS TR, 2002, J APPL PHYS, V91
[8]   Continuous-wave terahertz spectroscopy of biotin: vibrational anharmonicity in the far-infrared [J].
Korter, TM ;
Plusquellic, DF .
CHEMICAL PHYSICS LETTERS, 2004, 385 (1-2) :45-51
[9]  
MARKELZ AG, 2000, CHEM PHYS LETT, V320
[10]  
Moss T. S, 1961, OPTICAL PROPERTIES S