Styryl-lactone derivatives and alkaloids from Goniothalamus borneensis (Annonaceae)

被引：83

作者：

Cao, SG

Wu, XH

Sim, KY

Tan, BKH

Pereira, JT

Goh, SH

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

[2] Forest Res Ctr, Sabah, Malaysia

来源：

TETRAHEDRON | 1998年 / 54卷 / 10期

关键词：

D O I：

10.1016/S0040-4020(97)10422-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Twelve natural products, including two new compounds, goniothalesdiol 1a and goniothalactam 2, were isolated from the bark of the Malaysian tree Goniothalamus borneensis (Annonaceae) and evaluated for their cytotoxic activity. Their structures were elucidated by spectroscopy including 2D-NMR spectroscopy. 1a, which was semisynthesised from (+)-goniothalenol (3a), was related to several cytotoxic styryl-lactones (4-8) also isolated from this species. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：2143 / 2148

页数：6

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