Statistics and medicine: Drinking from the fire hose - Statistical issues in genomewide association studies

被引：125

作者：

Hunter, David J.

Kraft, Peter

机构：

[1] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA

[2] NCI, Canc Genet Markers Susceptibil Project, Bethesda, MD 20892 USA

[3] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2007年 / 357卷 / 05期

关键词：

D O I：

10.1056/NEJMp078120

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：436 / +

页数：3

共 4 条

[1] Replicating genotype-phenotype associations [J].

Chanock, Stephen J. ;

Manolio, Teri ;

Boehnke, Michael ;

Boerwinkle, Eric ;

Hunter, David J. ;

Thomas, Gilles ;

Hirschhorn, Joel N. ;

Abecasis, Goncalo ;

Altshuler, David ;

Bailey-Wilson, Joan E. ;

Brooks, Lisa D. ;

Cardon, Lon R. ;

Daly, Mark ;

Donnelly, Peter ;

Fraumeni, Joseph F., Jr. ;

Freimer, Nelson B. ;

Gerhard, Daniela S. ;

Gunter, Chris ;

Guttmacher, Alan E. ;

Guyer, Mark S. ;

Harris, Emily L. ;

Hoh, Josephine ;

Hoover, Robert ;

Kong, C. Augustine ;

Merikangas, Kathleen R. ;

Morton, Cynthia C. ;

Palmer, Lyle J. ;

Phimister, Elizabeth G. ;

Rice, John P. ;

Roberts, Jerry ;

Rotimi, Charles ;

Tucker, Margaret A. ;

Vogan, Kyle J. ;

Wacholder, Sholom ;

Wijsman, Ellen M. ;

Winn, Deborah M. ;

Collins, Francis S. .

NATURE, 2007, 447 (7145) :655-660

[2] Focus on research: What genome-wide association studies can do for medicine [J].

Christensen, Kaare ;

Murray, Jeffrey C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (11) :1094-1097

[3] Betting odds and genetic associations [J].

Thomas, DC ;

Clayton, DG .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2004, 96 (06) :421-423

[4] Assessing the probability that a positive report is false: An approach for molecular epidemiology studies [J].

Wacholder, S ;

Chanock, S ;

Garcia-Closas, M ;

El ghormli, L ;

Rothman, N .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2004, 96 (06) :434-442

← 1 →