Palatability of angiotensin II antagonists among nephropathic children

被引：21

作者：

Meier, Chiara M.

Simonetti, Giacomo D.

Ghiglia, Silvia

Fossali, Emilio

Salice, Patrizia

Limoni, Costanzo

Bianchetti, Mario G. ^{[1
]}

机构：

[1] San Giovanni Hosp, Dept Pediat, CH-6500 Bellinzona, Switzerland

[2] Univ Bern, Inselspital, Dept Pediat, CH-3010 Bern, Switzerland

[3] IRCCS, Fdn Osped Maggiore Policlin Mangiagalli & Regina, Milan, Italy

[4] Univ Appl Sci So Switzerland, Dept Econ & Social Sci, Manno, Switzerland

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 2007年 / 63卷 / 05期

关键词：

candesartan cilexetil; hypertension; irbesartan; losartan; palatability; telmisartan; valsartan;

D O I：

10.1111/j.1365-2125.2006.02814.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Aims Angiotensin II receptor blockers are widely prescribed in kidney disease. Among children, medication palatability is crucial for adherence. Methods Taste and smell acceptability of five angiotensin II receptor blockers were compared among 21 nephropathic children using a visual analogue scale palatability score. Results The score assigned to pulverized tablets of candesartan cilexetil was significantly higher than that assigned to pulverized tablets of irbesartan, losartan, telmisartan and valsartan. Conclusions the perspective of the nephropathic child, the taste of pulverized candesartan cilexetil is superior to that of irbesartan, losartan, telmisartan or valsartan.

引用

页码：628 / 631

页数：4

共 12 条

[1]

Conlin Paul R., 2000, J Clin Hypertens (Greenwich), V2, P253

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