First C3v-symmetrical calix[6](aza)crown

被引：67

作者：

Jabin, I

Reinaud, O

机构：

[1] Univ Havre, URCOM, Fac Sci & Tech, F-75068 Le Havre, France

[2] Univ Paris 05, UMR CNRS 8601, Chim & Biochim Pharmacol & Toxicol Lab, F-75270 Paris 06, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 09期

关键词：

D O I：

10.1021/jo026642h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first C-3nu-symmetrical calix[6](aza)crown 8 has been obtained in five steps from X6H3Me3 3. The key-step introduction of the triple bridge at the small rim has been achieved through reaction of a tris-arylsulfonamide derivative of tren 1 and tris-tosylcalix[6]arene 6. A H-1 NMR study has shown that the tripodal cap rigidifies the whole edifice, preventing ring inversion and constraining the calixarene core in a straight cone conformation.

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页码：3416 / 3419

页数：4

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