Binding kinetics of magnetic nonoparticles on latex beads studied by magnetorelaxometry

被引:17
作者
Eberbeck, D
Bergemann, C
Hartwig, S
Steinhoff, U
Trahms, L
机构
[1] Phys Tech Bundesanstalt, D-10587 Berlin, Germany
[2] Chemicell GMBH, Berlin, Germany
关键词
magnetic nanoparticles; latex; coupling kinetics; binding model; relaxometry; relaxation; concentration;
D O I
10.1002/aoc.758
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A system of magnetic nanoparticles (MNPs) and modified latex spheres was used serving as a model for studying binding reactions. The binding of MNPs on latex is estimated by the change of the magnetic relaxation properties of the MNP measured by a SQUID-based magnetorelaxometry measurement system. By fitting of subsequently recorded relaxation curves, the kinetics of the binding reactions, i.e. the evolution of the fraction of bound MNPs, was extracted. The signal of bound MNPs scales linearly with the concentration of latex beads. For low latex concentrations the kinetics are described by a simple aggregation model, providing information about the density and probability of bindings to the target surface. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
收藏
页码:542 / 547
页数:6
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