Single-molecule measurement in living cells

被引：8

作者：

Ichinose, J ^{[1
]}

Sako, Y ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Frontier Biosci, Labs Nanobiol, Suita, Osaka 5650871, Japan

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2004年 / 23卷 / 08期

关键词：

epidermal growth factor; intracellular signal transduction; single-molecule measurements; total internal reflection fluorescence microscopy;

D O I：

10.1016/j.trac.2004.06.001

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Single-molecule measurement techniques enable the dynamic behavior and reaction kinetics of individual biological molecules to be studied quantitatively at the single-molecule level with excellent spatial and temporal resolution. We discuss the general techniques used to visualize single molecules in living cells. (C) 2004 Published by Elsevier Ltd.

引用

页码：587 / 594

页数：8

共 38 条

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